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Skin Cancer Algorithm - Differential Diagnoses of Skin/Yellow Colored Lesions
Sebaceous Hyperplasia
- soft, yellowish, slightly raised, often umbilicated
- usually few in number measuring 2-4mm
- face especially forehead and cheeks
- usually middle-aged
Neurofibroma
- frequently sporadic (not associated with neurofibromatosis)
- soft, skin-coloured, slightly tan, elevated papule, sometimes polypoid
- usually 4-5mm and not usually over 1cm
Solar Elastosis
- older individuals, fair skinned with chronic sun exposure
- face, forehead usually
- usually patches of thickened yellowish changes - like chicken skin
- may have localized papule which is difficult to distinguish from skin cancer
Solitary Molluscum Contagiosum
- usually multiple skin-coloured waxy lesions
- central dell in multiple lesions
- normally seen in children or sexually transmitted in adults
- occasionally solitary skin-coloured papule often on the face without central depression
Benign Appendigeal Tumours: Trichoepithilioma
- usually solitary lesion but can be inherited and multiple
- skin coloured firm papule usually 2-8mm
- a ring of small whitish cyst on the periphery of the lesion
Benign Appendigeal Tumours: Syringoma
- usually in women
- may be solitary but usually multiple
- skin-coloured to yellowish small papule 2-5mm
- commonly on the upper cheeks or lower eyelids
- less common on abdomen and vulva
Leiomyoma
- may be skin colored papules when solitary
- most frequently a center of red brown tender papules, occasionaly painful
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